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In 2011, more than 300,000 patients in opioid treatment programs were given methadone as part of a treatment plan. Up to one-fourth of opioid-addicted patients receive methadone maintenance.
Detox diets that severely limit protein or that require fasting, for example, can result in fatigue. Long-term fasting can result in vitamin and mineral deficiencies. Ionic foot detoxes are said to rid the body of harmful toxins, but is this really possible? There is a lack of regulation and monitoring in the detox industry, and many detox foods and supplements may not have any scientific basis.
The higher the doses used, the more likely it is that withdrawal symptoms will be severe. A comorbid dependence on drugs and alcohol can create a unique constellation of withdrawal symptoms, which might exacerbate one another.